General information:
| Function | inosine-guanosine transporter (NT2) |
| Gene type | Protein coding gene |
| Transcript location | chr.36:769149-772095|- |
| Alternative SL | 772100(23),771994(2),771997(2),772055(2),772090(58),772071(6),771924(1) |
| Alternative polyA site | 769133(1),769143(3),769155(5),769166(4),769174(2),769138(1),769145(1),769152(1),769167(1) |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.36.T1940 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.36.1940 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0006190,GO:0006810,GO:0016020,GO:0016021,GO:0031226,GO:0005337
Associated PubMed publications:
- Carter NS, Drew ME, Sanchez M, Vasudevan G, Landfear SM, Ullman B. 2000. Cloning of a novel inosine-guanosine transporter gene from Leishmania donovani by functional rescue of a transport-deficient mutant. J Biol Chem 275: 20935-20941. [PUBMED]
- Alzahrani KJH, Ali JAM, Eze AA, Looi WL, Tagoe DNA, Creek DJ, Barrett MP, de Koning HP. 2017. Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy. Int J Parasitol Drugs Drug Resist 7: 206-226. [PUBMED]