General information:
| Function | metacaspase (MCA5) |
| Gene type | Protein coding gene |
| Transcript location | chr.35:680800-682862|- |
| Alternative SL | 682923(1),682748(1) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.35.T1580 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.35.1580 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0006508,GO:0006915,GO:0006979,GO:0008631,GO:0016540,GO:0070301,GO:0005759,GO:0005829,GO:0004197
Associated PubMed publications:
- Ambit A, Fasel N, Coombs GH, Mottram JC. 2008. An essential role for the Leishmania major metacaspase in cell cycle progression. Cell Death Differ 15: 113-122. [PUBMED]
- Gonzalez IJ, Desponds C, Schaff C, Mottram JC, Fasel N. 2007. Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity. Int J Parasitol 37: 161-172. [PUBMED]
- Lee N, Gannavaram S, Selvapandiyan A, Debrabant A. 2007. Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite Leishmania. Eukaryot Cell 6: 1745-1757. [PUBMED]