General information:
| Function | N-myristoyl transferase; putative (NMT) |
| Gene type | Protein coding gene |
| Transcript location | chr.32:23663-25237|- |
| Alternative SL | 25219(2) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.32.T0080 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.32.0080 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0006499,GO:0004379
Associated PubMed publications:
- Price HP, Menon MR, Panethymitaki C, Goulding D, McKean PG, Smith DF. 2003. Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites. J Biol Chem 278: 7206-7214. [PUBMED]
- Panethymitaki C, Bowyer PW, Price HP, Leatherbarrow RJ, Brown KA, Smith DF. 2006. Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major. Biochem J 396: 277-285. [PUBMED]
- Brannigan JA, Smith BA, Yu Z, Brzozowski AM, Hodgkinson MR, Maroof A, Price HP, Meier F, Leatherbarrow RJ, Tate EW et al. 2010. N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis. J Mol Biol 396: 985-999. [PUBMED]