General information:
| Function | silent information regulator 2; putative (SIR2RP1) |
| Gene type | Protein coding gene |
| Transcript location | chr.26:55050-56709|- |
| Alternative SL | 56697(3),56958(2) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.26.T0210 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.26.0210 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0051287,GO:0070403,GO:0017136,GO:0005634,GO:0004407,GO:0003950,GO:0003956,GO:0008270,GO:0006342,GO:0006281,GO:0006476
Associated PubMed publications:
- Purkait B, Singh R, Wasnik K, Das S, Kumar A, Paine M, Dikhit M, Singh D, Sardar AH, Ghosh AK et al. 2015. Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani. J Antimicrob Chemother 70: 1343-1356. [PUBMED]
- Vergnes B, Sereno D, Madjidian-Sereno N, Lemesre J, Ouaissi A. 2002. Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death. Gene 296: 139. [PUBMED]