General information:
Function | histone-lysine N-methyltransferase; putative (DOT1) |
Gene type | Protein coding gene |
Transcript location | chr.20:8045-9442|- |
Alternative SL | 9526(12),9371(1),9486(1) |
Alternative polyA site | 8018(1),8030(1),8039(1),8025(1),8052(1) |
Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.20.T0030 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.20.0030 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0018024,GO:0005634
Associated PubMed publications:
- Dejung M, Subota I, Bucerius F, Dindar G, Freiwald A, Engstler M, Boshart M, Butter F, Janzen CJ. 2016. Quantitative Proteomics Uncovers Novel Factors Involved in Developmental Differentiation of Trypanosoma brucei. PLoS Pathog 12: e1005439. [PUBMED]
- Janzen CJ, Hake SB, Lowell JE, Cross GAM. 2006. Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei. Mol Cell 23: 497-507. [PUBMED]