General information:
| Function | proliferative cell nuclear antigen (PCNA); putative |
| Gene type | Protein coding gene |
| Transcript location | chr.15:590695-592864|- |
| Alternative SL | 590566(3),590768(3),590642(73) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.15.T1450 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.15.1450 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0006275,GO:0030337,GO:0043626,GO:0003677
Associated PubMed publications:
- Tandon R, Chandra S, Baharia RK, Das S, Misra P, Kumar A, Siddiqi MI, Sundar S, Dube A. 2014. Characterization of the Proliferating Cell Nuclear Antigen of Leishmania donovani Clinical Isolates and Its Association with Antimony Resistance. Antimicrob Agents Chemother 58: 2997-3007. [PUBMED]
- Carnielli JBT, de Andrade HM, Pires SF, Chapeaurouge AD, Perales J, Monti-Rocha R, Carvalho SF, Ribeiro LP, Dietze R, Figueiredo SG et al. 2014. Proteomic analysis of the soluble proteomes of miltefosine-sensitive and -resistant Leishmania infantum chagasi isolates obtained from Brazilian patients with different treatment outcomes. Journal of proteomics 108: 198-208. [PUBMED]
- Yadav SP, Singh PK, Sharma P, Iqbal N, Kaur P, Sharma S, Singh TP. 2017. Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani. Biochim Biophys Acta 1865: 1395-1405. [PUBMED]
- Kumar D, Minocha N, Rajanala K, Saha S. 2009. The distribution pattern of proliferating cell nuclear antigen in the nuclei of Leishmania donovani. Microbiology 155: 3748-3757. [PUBMED]