General information:
| Function | mitochondrial DNA topoisomerase II (TOP2) |
| Gene type | Protein coding gene |
| Transcript location | chr.15:534814-539887|- |
| Alternative SL | 537650(1) |
| Alternative polyA site | Not found |
| Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.15.T1290 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.15.1290 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0005694,GO:0003677,GO:0003918,GO:0006265,GO:0005524
Associated PubMed publications:
- Das A, Dasgupta A, Sharma S, Ghosh M, Sengupta T, Bandopadhyay S, Majumder HK. 2001. Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy. Nucleic Acids Res 29: 1844-1851. [PUBMED]
- Hanke T, Ramiro MJ, Trigueros S, Roca J, Larraga V. 2003. Cloning, functional analysis and post-transcriptional regulation of a type II DNA topoisomerase from Leishmania infantum. A new potential target for anti-parasite drugs. Nucleic Acids Res 31: 4917-4928. [PUBMED]