General information:
Function | tryparedoxin peroxidase (TRYP7) |
Gene type | Protein coding gene |
Transcript location | chr.15:471565-473094|- |
Alternative SL | 470783(3),470922(1) |
Alternative polyA site | 469402(2),469386(1),469390(1),469392(1),469396(1) |
Other features | - |
Sequence:
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Here you can download sequence data derived from our research.
- LmjF.15.T1160 transcript sequence: This sequence includes the coding sequence within uppercase letters.
- LmjF.15.1160 protein sequence: Aminoacidic sequence of the corresponding protein.
Based on the updated L.major genome (Alonso et al. 2016):
Associated GO terms:
- GO:0016209,GO:0055114,GO:0016491,GO:0051920,GO:0045454
Associated PubMed publications:
- Carnielli JBT, de Andrade HM, Pires SF, Chapeaurouge AD, Perales J, Monti-Rocha R, Carvalho SF, Ribeiro LP, Dietze R, Figueiredo SG et al. 2014. Proteomic analysis of the soluble proteomes of miltefosine-sensitive and -resistant Leishmania infantum chagasi isolates obtained from Brazilian patients with different treatment outcomes. Journal of proteomics 108: 198-208. [PUBMED]
- Barr SD, Gedamu L. 2001. Cloning and characterization of three differentially expressed peroxidoxin genes from Leishmania chagasi. Evidence for an enzymatic detoxification of hydroxyl radicals. J Biol Chem 276: 34279-34287. [PUBMED]
- Flohe L, Budde H, Bruns K, Castro H, Clos J, Hofmann B, Kansal-Kalavar S, Krumme D, Menge U, Plank-Schumacher K et al. 2002. Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism. Arch Biochem Biophys 397: 324-335. [PUBMED]